Rankings computed from the game tables of this build: the numbers are the tables' own, the order follows them, and a balance patch reorders every list on the next build. Inscriptions with code-side effects are listed with their rule of thumb from the binary; archetype priorities are the only hand-authored part.
Best inscriptions: Major Stats
Agility
Inscription of Gloom +20% AgilityRare · 0.0455% per slot
Constitution
Inscription of Gloom +20% ConstitutionRare · 0.0455% per slot
Intelligence
Inscription of Gloom +20% IntelligenceRare · 0.0455% per slot
Perception
Inscription of Gloom +20% PerceptionRare · 0.0455% per slot
Strength
Inscription of Gloom +20% StrengthRare · 0.0455% per slot
Willpower
Inscription of Gloom +20% WillpowerRare · 0.0455% per slot
Best inscriptions: Combat
Attack Speed
High-grade Attack Speed Inscription +30% Attack SpeedRare · 0.0455% per slot
Mid-grade Attack Speed Inscription +20% Attack SpeedUncommon · 0.548% per slot
Low-grade Attack Speed Inscription +10% Attack SpeedCommon · 4.75% per slot
Cooldown Reduction
High-grade Cooldown Reduction Inscription Rare · 0.0455% per slot
Mid-grade Cooldown Reduction Inscription Uncommon · 0.548% per slot
Low-grade Cooldown Reduction Inscription Common · 4.75% per slot
Critical Chance
High-grade Critical Chance Inscription +15% Critical ChanceRare · 0.0455% per slot
Mid-grade Critical Chance Inscription +10% Critical ChanceUncommon · 0.548% per slot
Low-grade Critical Chance Inscription +5% Critical ChanceCommon · 4.75% per slot
Critical Damage Bonus
High-grade Critical Damage Inscription Rare · 0.0455% per slot
Mid-grade Critical Damage Inscription Uncommon · 0.548% per slot
Low-grade Critical Damage Inscription Common · 4.75% per slot
Dodge Chance
High-grade Dodge Chance Inscription +15% Dodge ChanceRare · 0.0455% per slot
Mid-grade Dodge Chance Inscription +10% Dodge ChanceUncommon · 0.548% per slot
Low-grade Dodge Chance Inscription +5% Dodge ChanceCommon · 4.75% per slot
Guard Chance
High-grade Guard Chance Inscription +30% Guard ChanceRare · 0.0455% per slot
Mid-grade Guard Chance Inscription +20% Guard ChanceUncommon · 0.548% per slot
Low-grade Guard Chance Inscription +10% Guard ChanceCommon · 4.75% per slot
Guard Damage Reduction
High-grade Guard Damage Reduction Inscription Rare · 0.0455% per slot
Mid-grade Guard Damage Reduction Inscription Uncommon · 0.548% per slot
Low-grade Guard Damage Reduction Inscription Common · 4.75% per slot
Hit Chance
High-grade Hit Chance Inscription +30% Hit ChanceRare · 0.0455% per slot
Mid-grade Hit Chance Inscription +20% Hit ChanceUncommon · 0.548% per slot
Low-grade Hit Chance Inscription +10% Hit ChanceCommon · 4.75% per slot
Life Steal
High-grade Life Steal Inscription +10% Life StealRare · 0.0455% per slot
Mid-grade Life Steal Inscription +7% Life StealUncommon · 0.548% per slot
Low-grade Life Steal Inscription +5% Life StealCommon · 4.75% per slot
Magic Attack Power
High-grade Magic Attack Inscription +30% Magic Attack PowerRare · 0.0455% per slot
Mid-grade Magic Attack Inscription +20% Magic Attack PowerUncommon · 0.548% per slot
Low-grade Magic Attack Inscription +10% Magic Attack PowerCommon · 4.75% per slot
Max Health Total
High-grade Max Health Inscription +30% Max Health TotalRare · 0.0455% per slot
Mid-grade Max Health Inscription +20% Max Health TotalUncommon · 0.548% per slot
Low-grade Max Health Inscription +10% Max Health TotalCommon · 4.75% per slot
Physical Attack Power
High-grade Physical Attack Inscription Rare · 0.0455% per slot
Mid-grade Physical Attack Inscription Uncommon · 0.548% per slot
Low-grade Physical Attack Inscription Common · 4.75% per slot
Best inscriptions: Resistances
Magic Resistance
High-grade Magic Resistance Inscription +25 Magic ResistanceRare · 0.0455% per slot
Mid-grade Magic Resistance Inscription +16 Magic ResistanceUncommon · 0.548% per slot
Low-grade Magic Resistance Inscription Common · 4.75% per slot
Physical Resistance
High-grade Physical Resistance Inscription Rare · 0.0455% per slot
Mid-grade Physical Resistance Inscription Uncommon · 0.548% per slot
Low-grade Physical Resistance Inscription Common · 4.75% per slot
Best inscriptions: Resources & Needs
Health Regeneration
High-grade Health Regeneration Inscription +0.3% Health RegenerationRare · 0.0455% per slot
Mid-grade Health Regeneration Inscription +0.2% Health RegenerationUncommon · 0.548% per slot
Low-grade Health Regeneration Inscription +0.1% Health RegenerationCommon · 4.75% per slot
Max Energy
High-grade Max Energy Inscription +30% Max EnergyRare · 0.0455% per slot
Mid-grade Max Energy Inscription +20% Max EnergyUncommon · 0.548% per slot
Low-grade Max Energy Inscription +10% Max EnergyCommon · 4.75% per slot
Max Weight
High-grade Max Weight Inscription +60% Max WeightRare · 0.0455% per slot
Inscription of the Carrier +50% Max WeightUncommon · 0.548% per slot
Mid-grade Max Weight Inscription +40% Max WeightUncommon · 0.548% per slot
Mood
Inscription of Gloom -3 MoodRare · 0.0455% per slot
Specials (effects that live in code, not in a stat column)
Capital Punishment Inscription Legendary Read the threshold straight off the enemy's max HP: a fifth of it is the execute line.
Inscription of Perfection Legendary All Talent increase by one level. Talent cannot exceed the maximum level, Genius.
Inscription of the Storm Legendary Every 10 physical attack power is 3 damage to each victim in the circle.
Inscription of Blitz Rare Acquire the blitz skill tree. Gain 5 Sub Skill Points.
Bloodshot Inscription Rare Each critical basic attack is 5 Bleeding stacks.
Inscription of Burst Rare Acquire the burst skill tree. Gain 5 Sub Skill Points.
Inscription of Challenge Rare Against an elite or a boss, multiply the hit by 1.20 before any other bonus dilutes it.
Inscription of Crumble Rare On a basic attack, multiply the hit by 1.25 before other bonuses dilute it.
Inscription of Death Throes Rare Every 10 percent of your own missing HP is +2 percentage points of damage.
Divine Inscription Rare Every 100 max HP is +10 Magic Attack Power.
Inscription of Elasticity Rare Every 100 HP you are missing gives 5 HP back per guard.
Inscription of Execution Rare Acquire the execution skill tree. Gain 5 Sub Skill Points.
Inscription of the Flint Rare Each critical basic attack is 5 Burning stacks.
Inscription of Fortress Rare Acquire the fortress skill tree. Gain 5 Sub Skill Points.
Giant's Inscription Rare Every 100 max HP is +10 Physical Attack Power.
Inscription of the Gold Mine Rare 10 critical hits is 100 gold. 200 of them exhausts the budget.
Inscription of the Guardian Rare Acquire the Guardian skill tree. Gain 5 Sub Skill Point.
Inscription of Harmony Rare Acquire the harmony skill tree. Gain 5 Sub Skill Points.
Inscription of the Jester Rare When a Dodge is triggered, inflict a random Debuffs on the attacker for 10 seconds.
Inscription of Magic Smite Rare Every 100 damage a basic attack lands adds 10 magic damage.
Inscription of Protection Rare Every 10 HP you are missing is 20 points of barrier.
Inscription of Recovery Rare Restores 30% of Energy to all allies upon entering a new floor.
Inscription of Reflection Rare Whatever number appears over your head, the attacker takes the same number.
Inscription of the Shockwave Rare Every 100 damage on the main target is 30 damage to each neighbour.
Sinking Inscription Rare Every 10 percent of the target's missing HP is +12 percentage points of damage on the proc.
Smash Inscription Rare When you inflict a Stun-category effect, you also inflict Vulnerable for the same duration.
Inscription of Stake Rare Acquire the Stake support skill tree. Gain 5 Sub Skill Point.
Inscription of Tide Rare Acquire the tide skill tree. Gain 5 Sub Skill Points.
Inscription of Warrior Rare Acquire the warrior skill tree. Gain 5 Sub Skill Points.
Inscription of Blunt Uncommon Acquire the blunt skill tree. Gain 5 Main Skill Points.
Inscription of Bow Uncommon Acquire the bow skill tree. Gain 5 Main Skill Points.
Inscription of Embers Uncommon 3 basic attacks is one payout of 2 Burning stacks.
Inscription of Excessive Bleeding Uncommon 3 basic attacks is one payout of 2 Bleeding stacks.
Inscription of Fire magic Uncommon Acquire the fire magic skill tree. Gain 5 Main Skill Points.
Inscription of Greatsword Uncommon Acquire the greatsword skill tree. Gain 5 Main Skill Points.
Inscription of the Heavy Plumb Uncommon Every 10 points of carried Weight is +1.5 percent damage.
Inscription of Nature magic Uncommon Acquire the nature magic skill tree. Gain 5 Main Skill Points.
Inscription of Shield Uncommon Acquire the shield skill tree. Gain 5 Main Skill Points.
Inscription of Spear Uncommon Acquire the spear skill tree. Gain 5 Main Skill Points.
Inscription of the Sprouting Shell Uncommon 60 Energy is 1 Shell.
Inscription of Sword Uncommon Acquire the sword skill tree. Gain 5 Main Skill Points.
Inscription of Water magic Uncommon Acquire the water magic skill tree. Gain 5 Main Skill Points.
Best items for needs and regeneration (on use)
Attack Speed
Attack Speed Potion +30% Attack Speedbuff
Energy Regeneration
Royal Jelly +0.2 Energy Regenerationbuff
Gloth Egg Omelet +0.1 Energy Regenerationbuff
Monster Barbecue +0.08 Energy Regenerationbuff
Hit Chance
Accuracy Potion +30% Hit Chancebuff
Life Steal
Vampire Potion +10% Life Stealbuff
Magic Attack Power
Magical Attack Potion +30% Magic Attack Powerbuff
Hell Leech +20% Magic Attack Powerbuff
Magic Resistance
Magic Resistance Potion +25 Magic Resistancebuff
Max Weight
Weight Potion +60% Max Weightbuff
Mood
Gloth Egg Omelet +9 Moodbuff
Meat Skewer +9 Moodbuff
Slime Pudding +8 Moodbuff
Mushroom Skewer +7 Moodbuff
Monster Barbecue +7 Moodbuff
Movement Speed
Swift Potion +30% Movement Speedbuff
Physical Attack Power
Physical Resistance
Metal Skin Potion buff
Best in slot: Fire mage
Magic attack power first. A staff is two-handed, so the off-hand stays empty.
Weapon ranked by Magic Attack Power
Red Crystal Bloodwood Staff Rare
Red Crystal Carapace Staff Rare
Fire Arcron Staff Uncommon
Helmet ranked by Max Health Total
Iron Helmet +113 Max Health TotalCommon
Arcron Helmet +95 Max Health TotalCommon
Copper Helmet +80 Max Health TotalCommon
Armor ranked by Max Health Total
Iron Armor +225 Max Health TotalCommon
Arcron Armor +191 Max Health TotalCommon
Copper Armor +158 Max Health TotalCommon
Ammo ranked by Physical Attack Power
Arcron Arrow Common
Copper Arrow Common
Bloodwood Arrow Rare
Best in slot: Water mage
Magic attack power first; the water tree's own skills decide the rest.
Weapon ranked by Magic Attack Power
Blue Crystal Bloodwood Staff Rare
Blue Crystal Carapace Staff Rare
Water Arcron Staff Uncommon
Helmet ranked by Max Health Total
Iron Helmet +113 Max Health TotalCommon
Arcron Helmet +95 Max Health TotalCommon
Copper Helmet +80 Max Health TotalCommon
Armor ranked by Max Health Total
Iron Armor +225 Max Health TotalCommon
Arcron Armor +191 Max Health TotalCommon
Copper Armor +158 Max Health TotalCommon
Ammo ranked by Physical Attack Power
Arcron Arrow Common
Copper Arrow Common
Bloodwood Arrow Rare
Best in slot: Sword and shield
Physical attack power on the weapon, the best shield in the off-hand.
Weapon ranked by Physical Attack Power
Arcron Mace Rare
Arcron Sword Rare
Copper Mace Common
Off-hand ranked by Max Health Total
Arcron Shield +95 Max Health TotalCommon
Copper Shield +80 Max Health TotalCommon
Bloodwood Shield +74 Max Health TotalRare
Helmet ranked by Physical Attack Power
Fortified Bone Helmet Common
Armor ranked by Physical Attack Power
Fortified Bone Armor Common
Ammo ranked by Physical Attack Power
Arcron Arrow Common
Copper Arrow Common
Bloodwood Arrow Rare
Best in slot: Two-handed fighter
Physical attack power; no off-hand.
Weapon ranked by Physical Attack Power
Iron Great Sword Common
Arcron Greatsword Rare
Arcron Spear Rare
Helmet ranked by Physical Attack Power
Fortified Bone Helmet Common
Armor ranked by Physical Attack Power
Fortified Bone Armor Common
Ammo ranked by Physical Attack Power
Arcron Arrow Common
Copper Arrow Common
Bloodwood Arrow Rare
Best in slot: Archer
Physical attack power on the bow; arrows are the ammo slot.
Weapon ranked by Physical Attack Power
Arcron Bow Rare
Copper Bow Common
Bloodwood Bow Rare
Helmet ranked by Physical Attack Power
Fortified Bone Helmet Common
Armor ranked by Physical Attack Power
Fortified Bone Armor Common
Ammo ranked by Physical Attack Power
Arcron Arrow Common
Copper Arrow Common
Bloodwood Arrow Rare
Best in slot: Tank
Max health on every piece, a shield in the off-hand.
Weapon ranked by Physical Attack Power
Arcron Mace Rare
Arcron Sword Rare
Copper Mace Common
Off-hand ranked by Max Health Total
Arcron Shield +95 Max Health TotalCommon
Copper Shield +80 Max Health TotalCommon
Bloodwood Shield +74 Max Health TotalRare
Helmet ranked by Max Health Total
Iron Helmet +113 Max Health TotalCommon
Arcron Helmet +95 Max Health TotalCommon
Copper Helmet +80 Max Health TotalCommon
Armor ranked by Max Health Total
Iron Armor +225 Max Health TotalCommon
Arcron Armor +191 Max Health TotalCommon
Copper Armor +158 Max Health TotalCommon
Ammo ranked by Physical Attack Power
Arcron Arrow Common
Copper Arrow Common
Bloodwood Arrow Rare